Chemistry:Normethadone

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Short description: Synthetic opioid
Normethadone
Normethadone.png
Clinical data
Trade namesCophylac
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability100%
Metabolismliver
Elimination half-life14 days
ExcretionUrine
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC20H25NO
Molar mass295.426 g·mol−1
3D model (JSmol)
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Normethadone (INN, BAN; brand names Ticarda, Cophylac, Dacartil, Eucopon, Mepidon, Noramidone, Normedon, and others), also known as desmethylmethadone or phenyldimazone, is a synthetic opioid analgesic and antitussive agent.[citation needed] Normethadone is listed under the Single Convention on Narcotic Drugs 1961 and is a Schedule I Narcotic controlled substance in the United States, with a DEA ACSCN of 9635 and an annual manufacturing quota of 2 grams. It has an effective span of action for about 14 days, and is 12 to 20 times stronger than morphine. [1] The salts in use are the hydrobromide (free base conversion ratio 0.785), hydrochloride (0.890), methyliodide (0.675), oxalate (0.766), picrate (0.563), and the 2,6-ditertbutylnapthalindisulphonate (0.480).[2]

See also

References

  1. "Quotas - 2014". Diversion Control Division. U.S. Department of Justice, Drug Enforcement Administration. http://www.deadiversion.usdoj.gov/fed_regs/quotas/2014/fr0825.htm. 
  2. "Normethadone". The A-Z encyclopedia of alcohol and drug abuse. Parkland, Fla.: Brown Walker Press. 2002. p. 470. ISBN 978-1-58112-404-0. https://books.google.com/books?id=4yaGePenGKgC&q=Normethadone&pg=PA469.