Chemistry:α-Zearalenol
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Short description: Chemical compound
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| Other names | alpha-Zearalenol; trans-Zearalenol; 2,4-Dihydroxy-6-(6α,10-dihydroxy-trans-1-undecenyl)benzoic acid μ-lactone |
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| Formula | C18H24O5 |
| Molar mass | 320.385 g·mol−1 |
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α-Zearalenol is a nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in Fusarium spp.[1] It is the α-epimer of β-zearalenol.[2] Along with β-zearalenol, it is a major metabolite of zearalenone formed mainly in the liver but also to a lesser extent in the intestines during first-pass metabolism.[2][3] A relatively low proportion of β-zearalenol is metabolized from zearalenone compared to α-zearalenol in humans.[3] α-Zearalenol is about three to four times more potent as an estrogen relative to zearalenone.[1]
See also
- Taleranol (β-zearalanol)
- Zeranol (α-zearalanol)
- Zearalanone
References
- ↑ 1.0 1.1 Fusarium: Mycotoxins, Taxonomy, Pathogenicity. Elsevier Science. 28 June 2014. pp. 85–. ISBN 978-1-4832-9785-9. https://books.google.com/books?id=_1KeBQAAQBAJ&pg=PA85.
- ↑ 2.0 2.1 Mycotoxins in Food: Detection and Control. Woodhead Publishing. 2004. pp. 356–. ISBN 978-1-85573-733-4. https://books.google.com/books?id=CZ3iEhPeejoC&pg=PA356.
- ↑ 3.0 3.1 Fusarium Toxins in Cereals: A Risk Assessment. Nordic Council of Ministers. 1998. pp. 61–. ISBN 978-92-893-0149-7. https://books.google.com/books?id=jU5Wx8LkZHUC&pg=PA61.
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