Chemistry:Echinopsidine
From HandWiki
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| Other names | Echinopsidine Iodide |
| Routes of administration | Oral |
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| Formula | C10H12N2 |
| Molar mass | 160.22 g/mol g·mol−1 |
Echinopsidine (Adepren) is an antidepressant that was under development in Bulgaria for the treatment of depression.[1][2] It increases serotonin, norepinephrine, and dopamine levels in the brain and is believed to act as a monoamine oxidase inhibitor (MAOI).[3][4][5] Echinopsidine is found naturally in Echinops echinatus along with the related alkaloids echinopsine and echinozolinone.[6]
See also
References
- ↑ Guliamov MG (1982). "[Experience with the use of new Bulgarian psychotropic drugs]" (in Russian). Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952) 82 (11): 115–22. PMID 6758442.
- ↑ Guliamov MG (1986). "[Comparative evaluation of the therapeutic efficacy of the antidepressants adepren, linamiphen and emovit]" (in Russian). Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952) 86 (4): 582–7. PMID 3716711.
- ↑ Tiutiulkova N; Gorancheva Iu (1978). "[Effect of adepren on the cerebral concentration of serotonin]" (in Bulgarian). Eksperimentalna Meditsina I Morfologiia 17 (2): 83–5. PMID 658004.
- ↑ "[Effect of adepren on the behavior and brain catecholamines of rats in an open field setup]" (in Bulgarian). Eksperimentalna Meditsina I Morfologiia 15 (1): 42–6. 1976. PMID 1269462.
- ↑ Tiutiulkova NI; Gorancheva IuI (1975). "[Excretion of dopamine, noradrenaline, adrenaline, vanilmandelic acid and 5-hydroxyindoleacetic acid in the urine of volunteers treated with adepren]" (in Bulgarian). Eksperimentalna Meditsina I Morfologiia 14 (4): 187–9. PMID 1222713.
- ↑ Indian Medicinal Plants An Illustrated Dictionary. Springer-Verlag Berlin Heidelberg. 2007. ISBN 0-387-70637-2. https://books.google.com/?id=gMwLwbUwtfkC&lpg=PA230&dq=Echinopsidine&pg=PA230#v=onepage&q=&f=false.
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