Chemistry:Estradiol 3-propionate
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Short description: Chemical compound
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| Other names | Estradiol 3-propanoate; 3-Propanoylestradiol; 3,17β-Hydroxyestra-1,3,5(10)-trien-3-yl propionate |
| Routes of administration | Intramuscular injection, vaginal[1] |
| Drug class | Estrogen; Estrogen ester |
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| Formula | C21H28O3 |
| Molar mass | 328.452 g·mol−1 |
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Estradiol 3-propionate, or 3-propanoylestradiol, also known as estra-1,3,5(10)-triene-3,17β-diol 3-propionate, is a semisynthetic, steroidal estrogen that was never marketed.[1][2] It is an estrogen ester, specifically, a propionic acid ester of estradiol, and acts as a prodrug to it in vivo.[1][2] The chemical structure of estradiol 3-propionate is contained within estradiol dipropionate, estrapronicate, and orestrate,[3] all of which are also estradiol esters.[2]
See also
References
- ↑ 1.0 1.1 1.2 "Design of an intravaginal ring for the controlled delivery of 17 beta-estradiol as its 3-acetate ester". J Control Release 61 (3): 319–28. 1999. doi:10.1016/s0168-3659(99)00148-0. PMID 10477804.
- ↑ 2.0 2.1 2.2 J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 898. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=RA1-PA129.
- ↑ PubChem. "Estradiol" (in en). https://pubchem.ncbi.nlm.nih.gov/compound/5757.
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