Chemistry:Estrone benzoate
From HandWiki
Short description: Chemical compound
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| Other names | Ketohydroxyestrin benzoate; Estra-1,3,5(10)-trien-3-ol-17-one 3-benzoate |
| Routes of administration | Intramuscular injection |
| Drug class | Estrogen; Estrogen ester |
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| Formula | C25H26O3 |
| Molar mass | 374.480 g·mol−1 |
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Estrone benzoate, or estrone 3-benzoate, is a synthetic estrogen and estrogen ester – specifically, the C3 benzoate ester of estrone – which was first reported in 1932 and was never marketed.[1][2][3][4] It led to the development in 1933 of the more active estradiol benzoate, the first estradiol ester to be introduced for medical use.[5][6][7][8]
See also
References
- ↑ The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 900–. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA900.
- ↑ Clinical Endocrinology: Theory and Practice. Springer Science & Business Media. 6 December 2012. pp. 512–. ISBN 978-3-642-96158-8. https://books.google.com/books?id=DAgJCAAAQBAJ&pg=PA512.
- ↑ "Effective Absorption of Hormones". British Medical Journal 1 (4024): 371–373. February 1938. doi:10.1136/bmj.1.4024.371. PMID 20781252.
- ↑ "Über isomere Follikelhormone. Untersuchungen über das weibliche Sexualhormon, 7. Mitteilung.". Hoppe-Seyler's Zeitschrift für physiologische Chemie 208 (4): 129–148. 1932. doi:10.1515/bchm2.1932.208.4.129. ISSN 0018-4888.
- ↑ Estrogens and Antiestrogens I: Physiology and Mechanisms of Action of Estrogens and Antiestrogens. Springer Science & Business Media. 6 December 2012. pp. 8–. ISBN 978-3-642-58616-3. https://books.google.com/books?id=0BfrCAAAQBAJ&pg=PA8.
- ↑ "The activation of female sex hormones: Mono-esters of alpha-oestradiol". The Biochemical Journal 32 (8): 1273–1280. August 1938. doi:10.1042/bj0321273b. PMID 16746750.
- ↑ The Evolution of Drug Discovery: From Traditional Medicines to Modern Drugs. John Wiley & Sons. 16 May 2011. p. 175. ISBN 978-3-527-32669-3. https://books.google.com/books?id=iDNy0XxGqT8C&pg=PA175. Retrieved 20 May 2012.
- ↑ "The effect of oestrogenic hormones on lactation and on the phosphatase of the blood and milk of the lactating cow". The Biochemical Journal 30 (12): 2262–2272. December 1936. doi:10.1042/bj0302262. PMID 16746289.[yes|permanent dead link|dead link}}]
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