Chemistry:N,N-Didesmethyltamoxifen

Short description: Chemical compound

N,N-Didesmethyltamoxifen

Clinical data
Other names	Dinortamoxifen
Identifiers
IUPAC name 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]ethanamine
CAS Number	80234-20-4
PubChem CID	3036172
ChemSpider	2300247
KEGG	C16548
ChEBI	CHEBI:80556
ChEMBL	ChEMBL1743350
Chemical and physical data
Formula	C24H25NO
Molar mass	343.470 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC/C(=C(\C1=CC=CC=C1)/C2=CC=C(C=C2)OCCN)/C3=CC=CC=C3
InChI InChI=1S/C24H25NO/c1-2-23(19-9-5-3-6-10-19)24(20-11-7-4-8-12-20)21-13-15-22(16-14-21)26-18-17-25/h3-16H,2,17-18,25H2,1H3/b24-23- Key:MCJKBWHDNUSJLW-VHXPQNKSSA-N

N,N-Desmethyltamoxifen is a metabolite of tamoxifen, a selective estrogen receptor modulator (SERM). It is formed from N-desmethyltamoxifen and is an intermediate in the conversion of tamoxifen and N-desmethyltamoxifen into norendoxifen (4-hydroxy-N,N-desmethyltamoxifen), an active metabolite of tamoxifen.