Chemistry:Estradiol dibenzoate
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Short description: Synthetic estrogen
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| Other names | EDB; Estradiol 3,17β-dibenzoate; Estra-1,3,5(10)-triene-3,17β-diol 3,17β-dibenzoate |
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| Formula | C32H32O4 |
| Molar mass | 480.604 g·mol−1 |
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Estradiol dibenzoate (EDB), also known as estradiol 3,17β-dibenzoate, is an estrogen ester which was developed in the 1930s and was never marketed.[1][2][3][4][5][6][7] It is the C3 and C17β benzoate diester of estradiol.[1] Estradiol dibenzoate has a longer duration of action than estradiol benzoate (estradiol 3-benzoate) by depot injection.[2][3][4][5][6][7]
See also
References
- ↑ 1.0 1.1 ChemPRODUCTindex, Volumes 1-2. De Gruyter. 1976. pp. 881–. ISBN 978-3-11-002141-7. OCLC 2619908. https://books.google.com/books?id=KaAgAAAAMAAJ&pg=PA881.
- ↑ 2.0 2.1 "Effective Absorption of Hormones". British Medical Journal 1 (4024): 371–373. February 1938. doi:10.1136/bmj.1.4024.371. PMID 20781252.
- ↑ 3.0 3.1 "Rate of Absorption of Esters of Oestrone and Oestradiol as Determined by Feather Tests". Journal of Endocrinology 3 (1): 288–291. March 1942. doi:10.1677/joe.0.0030288. ISSN 0022-0795.
- ↑ 4.0 4.1 "Relative duration of action of various esters of oestrone, oestradiol and oestriol". The Biochemical Journal 31 (4): 579–585. April 1937. doi:10.1042/bj0310579. PMID 16746375.
- ↑ 5.0 5.1 "The activation of female sex hormones: alpha-Oestradiol and its di-esters". The Biochemical Journal 32 (4): 725–732. April 1938. doi:10.1042/bj0320725. PMID 16746680.
- ↑ 6.0 6.1 "Factors influencing the effectiveness of administered hormones". Proceedings of the Royal Society of London. Series B, Biological Sciences 124 (836): 279–298. 7 December 1937. doi:10.1098/rspb.1937.0086. ISSN 2053-9193. Bibcode: 1937RSPSB.124..279D.
- ↑ 7.0 7.1 "Effect of Androgens and Estrogens on Birds". Vitamins & Hormones. 2. Elsevier. 1944. pp. 361–408. doi:10.1016/S0083-6729(08)60290-3. ISBN 9780127098029.
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