Chemistry:P-Methoxyfentanyl

From HandWiki
Short description: Synthetic opioid analgesic


P-Methoxyfentanyl
P-methoxyfentanyl.svg
P-methylfentanyl.png
Identifiers
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC23H30N2O2
Molar mass366.505 g·mol−1
3D model (JSmol)

para-Methoxyfentanyl or p-methoxyfentanyl or 4-methoxyfentanyl is a potent short-acting synthetic opioid analgesic drug. It is an analog of fentanyl, with similar effects but slightly lower potency.[1][2]

See also

References

  1. Higashikawa, Yoshiyasu (2008). "Studies on 1-(2-phenethyl)-4-(N-propionylanilino) piperidine (fentanyl) and its related compounds. VI. Structure-analgesic activity relationship for fentanyl, methyl-substituted fentanyls and other analogues". Forensic Toxicology 26 (1): 1-5. doi:10.1007/s11419-007-0039-1. 
  2. Sinhorini, Luiz FC (2021). "Synthetic fentanyls evaluation and characterization by infrared spectroscopy employing in silico methods". Computational and Theoretical Chemistry 1204: 113378. doi:10.1016/j.comptc.2021.113378. 

Further reading

  • "Studies on 1-(2-phenethyl)-4-(N-propionylanilino)piperidine (fentanyl) and its related compounds. VI. Structure-analgesic activity relationship for fentanyl, methyl-substituted fentanyls and other analogues". Forensic Toxicology 26 (1): 1–5. June 2008. doi:10.1007/s11419-007-0039-1. 
  • "Fentanyl receptor assay. II. Utilization of a radioreceptor assay for the analysis of fentanyl analogs in urine". J Anal Toxicol 16 (1): 36–41. 1992. doi:10.1093/jat/16.1.36. PMID 1322477. 
  • "Evaluation of new compounds for opioid activity: 1987 annual report". NIDA Res. Monogr. 81: 543–90. 1988. PMID 3136388. 
  • "Dependence studies of new compounds in the rhesus monkey, rat, and mouse, 1987". NIDA Res. Monogr. 81: 485–542. 1988. PMID 3136386. 
  • "Carbon-13 nuclear magnetic resonance spectra of fentanyl analogs". Journal of Heterocyclic Chemistry 26 (3): 677–686. 2009. doi:10.1002/jhet.5570260329.