Chemistry:Dazadrol
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Dazadrol is a synthetic antidepressant developed by Schering Corp in the late 1960s. It acts primarily as a noradrenaline reuptake inhibitor, increasing concentrations of noradrenaline in the synaptic cleft, which is believed to underlie its antidepressant effects.[1][2][3]
Dazadrol is classified as a pyridinemethanol derivative and has been studied for its impact on neurological function and mood. In addition to its antidepressant activity, preclinical studies in rats have shown that it inhibits both basal and induced gastric acid secretion, indicating potential gastrointestinal effects.[1][3][4][2]
See also
References
- ↑ 1.0 1.1 "Dazadrol". Inxight Drugs. The National Center for Advancing Translational Sciences (NCATS). https://drugs.ncats.io/drug/9U27285V5R.
- ↑ 2.0 2.1 "Blockade of noradrenaline uptake and inhibition of gastric acid secretion by 2-[p-chlorophenyl-2-(pyridyl)hydroxymethyl] imidazoline maleate (Sch-12650)". The Journal of Pharmacy and Pharmacology 22 (5): 387–388. May 1970. doi:10.1111/j.2042-7158.1970.tb08548.x. PMID 4393004.
- ↑ 3.0 3.1 "[Pharmacological properties of a new potential antidepressant: ((p-chlorophenyl)-2-(pyridyl)-hydroxymethyl) imidazoline (SCH 12.650)]" (in French). Therapie 26 (4): 805–821. 1971. PMID 5119131.
- ↑ Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. 1996. ISBN 978-0-412-46630-4. https://books.google.com/books?id=A0THacd46ZsC.
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