Chemistry:Isopropoxate
From HandWiki
Isopropoxate is an anesthetic drug related to etomidate, which has been sold as a designer drug as an active ingredient in e-cigarette liquids marketed under names such as space oil or kpods. While the related n-propyl ester propoxate has been known since the 1970s, the isopropyl ester isopropoxate is a novel compound which was previously unknown prior to its detection as a designer drug in China in January 2024. It was added to the controlled drug list in China in July 2024, following which a number of other etomidate analogues have continued to appear.[1][2][3][4]
References
- ↑ "A recent increasing occurrence of etomidate and propoxate/isopropoxate misuse". Clinical Toxicology 63 (1): 65–67. January 2025. doi:10.1080/15563650.2024.2423834. PMID 39600244.
- ↑ "Identification of a novel imidazole-derived GABA agonist isopropoxate: simultaneous detection and quantification of imidazole-derived analogs from human hairs in abused cases by LC-MS/MS". Forensic Toxicology 43 (2): 190–205. July 2025. doi:10.1007/s11419-024-00707-y. PMID 39668300.
- ↑ "Acquired 11β-Hydroxylase deficiency in etomidate and (Iso)propoxate abusers: A nascent endocrine condition". Steroids 220. August 2025. doi:10.1016/j.steroids.2025.109639. PMID 40451601.
- ↑ Substance details: Isopropoxate. UNODC, 2025
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