Chemistry:SL-164

From HandWiki

SL-164, also known as dicloqualone or DCQ, is an analogue of methaqualone developed in the late 1960s by a team at Sumitomo.[1] SL-164 has similar sedative, hypnotic[2] and properties to the parent compound, but was never marketed for clinical use, due to higher risk of convulsions. Like other 4-substituted analogues, such as methylmethaqualone, SL-164 may cause seizures.[3]

References

  1. "Compositions And Methods For Tranquilizing With Substituted 3-Phenyl-4-Quinazolinone Derivatives" US patent 3651230
  2. "Pharmacological studies on 2-methyl-3(2'-methyl-4'-chlorophenyl)-5-chloro-4[H)-quinazolinone (SL-164)". Arzneimittel-Forschung 19 (12): 1945–9. December 1969. PMID 4985336. 
  3. "[Substituted 4-Quinazolinone Derivatives As Hypnotics]" (in German). Arzneimittel-Forschung 13: 688–701. August 1963. PMID 14085923.