Chemistry:ICI-190,622

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Short description: Anxiolytic drug
ICI-190,622
ICI-190,622.svg
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC15H17N5O
Molar mass283.335 g·mol−1
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

ICI-190,622 is an anxiolytic drug used in scientific research. It is a pyrazolopyridine derivative, related to other anxiolytic compounds such as tracazolate, and more distantly to zaleplon. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic.[1][2]

See also

References

  1. "Preclinical studies with pyrazolopyridine non-benzodiazepine anxiolytics: ICI 190,622". Pharmacology Biochemistry and Behavior 29 (4): 775–9. April 1988. doi:10.1016/0091-3057(88)90205-5. PMID 2901116. 
  2. "Synthesis and structure-activity relationships of a series of anxioselective pyrazolopyridine ester and amide anxiolytic agents". Journal of Medicinal Chemistry 32 (12): 2561–73. December 1989. doi:10.1021/jm00132a011. PMID 2573731.