Chemistry:Alphenal
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Short description: Chemical compound
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| Other names | 5-Phenyl-5-allylbarbituric acid |
| Routes of administration | Oral |
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| Formula | C13H12N2O3 |
| Molar mass | 244.250 g·mol−1 |
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Alphenal (Alphenal, Efrodal, Prophenal, Sanudorm), also known as 5-allyl-5-phenylbarbituric acid, is a barbiturate derivative developed in the 1920s.[1] It has primarily anticonvulsant properties, and was used occasionally for the treatment of epilepsy or convulsions, although not as commonly, as better known barbiturates such as phenobarbital.[2][3] [4][5]
LD50: Mouse (Oral): 280 mg/kg
References
- ↑ "Verfahren zur Darstellung von C,C-disubstituierten Barbitursaeuren" DE patent 526854, issued 11 June 1931, assigned to Hoffmann La Roche
- ↑ "Nuovi Barbiturici Alogenati Farmaco". Ediozione Scientifica 17 (6): 390–413. 1962.
- ↑ "Psychopharmacological Agents". Kirk-Othmer Encyclopedia of Chemical Technology. December 2000. doi:10.1002/0471238961.1619250313011820.a01. ISBN 0471238961.
- ↑ Analytical Toxicology: For Clinical, Forensic, and Pharmaceutical Chemists. Walter de Gruyter. 1997. p. 348. ISBN 978-3-11-010731-9. https://books.google.com/books?id=ZhYtynyC4kAC&pg=PA348. Retrieved 19 May 2012.
- ↑ Fundamentos de síntesis de fármacos. Edicions Universitat Barcelona. 28 January 2005. p. 161. ISBN 978-84-475-2876-9. https://books.google.com/books?id=Ib_wd3JC79QC&pg=PT161. Retrieved 19 May 2012.
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