Chemistry:Benzobarbital

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Short description: Chemical compound
Benzobarbital
Benzobarbital.svg
Benzobarbital ball-and-stick.png
Clinical data
Other namesBenzonal
ATC code
  • none
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC19H16N2O4
Molar mass336.347 g·mol−1
3D model (JSmol)
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Benzobarbital (Benzonal) is a barbiturate derivative. It has anticonvulsant effects and has been used for the treatment of epilepsy. [1]

It has similar liver enzyme inducing effects to the closely related drug phenobarbital, which may be exploited in some clinical applications. [2] [3]

References

  1. "[Pharmacological characteristics of an anti-convulsive drug Benzonal and the evaluation of its therapeutic effectiveness (review of the literature)]" (in russian). Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova 89 (11): 136–45. 1989. PMID 2696306. 
  2. "[The advantages of benzonal as an inducer of the liver mono-oxygenase enzyme system compared to phenobarbital]" (in russian). Eksperimental'naia i Klinicheskaia Farmakologiia 55 (1): 68–71. 1992. PMID 1305441. 
  3. "[Benzonal--a phenobarbital-type of inducer of the mono-oxygenase system]" (in russian). Biulleten' Eksperimental'noi Biologii I Meditsiny 111 (2): 163–5. February 1991. OCLC 613807502. PMID 1854958.