Chemistry:1T-LSD

From HandWiki

1T-LSD, also known as 1-(thiophene-2-carbonyl)-LSD or as SYN-L-021, is an acylated derivative of lysergic acid diethylamide (LSD), which has been sold as a designer drug.[1][2] It was first identified in Japan in 2023 on blotter paper misrepresented as containing 1D-LSD, but which on analysis was determined to contain 1T-LSD instead.[3] It was also detected in Germany around the same time.[4]

Use and effects

A 150 μg dose of 1T-LSD is said to be equivalent to 100 μg LSD.[2] Doses of 87 to 100 μg 1T-LSD have been encountered in blotter tabs.[1]

Interactions

Chemistry

Analogues

Analogues of 1T-LSD include ALD-52 (1A-LSD), 1P-LSD, 1B-LSD, 1V-LSD, 1DD-LSD, and 1T-AL-LAD, among others.

Society and culture

Canada

1T-LSD is not a controlled substance in Canada as of 2025.[5]

United States

1T-LSD is not an explicitly controlled substance in the United States.[6] However, it could be considered a controlled substance under the Federal Analogue Act if intended for human consumption.

See also

References

  1. ↑ 1.0 1.1 "1T-LSD" (in ru). 21 August 2023. https://aipsin.com/newsubstance/1188/. 
  2. ↑ 2.0 2.1 "1T-LSD" (in ru). https://aipsin.com/newsubstance/1750/. 
  3. ↑ "Identification of 1-(thiophene-2-carbonyl)-LSD from blotter paper falsely labeled "1D-LSD"". Forensic Toxicology 42 (1): 93–101. July 2023. doi:10.1007/s11419-023-00668-8. PMID 37421500. 
  4. ↑ "New psychoactive substances - the current situation in Europe". European Drug Report. European Union Drugs Agency (EUDA). 2024. https://www.euda.europa.eu/sites/default/files/pdf/31883_en.pdf?606797. 
  5. ↑ "Controlled Drugs and Substances Act". https://laws-lois.justice.gc.ca/eng/acts/c-38.8/FullText.html. 
  6. ↑ Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026), United States: U.S. Department of Justice: Drug Enforcement Administration (DEA): Diversion Control Division, January 2026, https://www.deadiversion.usdoj.gov/schedules/orangebook/orangebook.pdf 



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