Chemistry:Estradiol diacetate

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Short description: Chemical compound
Estradiol diacetate
Estradiol diacetate.svg
Clinical data
Other namesEDA; Estradiol 3,17β-diacetate; NSC-106559
Drug classEstrogen; Estrogen ester
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC22H28O4
Molar mass356.462 g·mol−1
3D model (JSmol)

Estradiol diacetate (EDA), or estradiol 3,17β-diacetate, is an estrogen and an estrogen ester—specifically, the C3 and C17β diacetate ester of estradiol—which was never marketed.[1][2][3][4] It is related to the estradiol monoesters estradiol acetate (estradiol 3-acetate; Femtrace) and estradiol 17β-acetate.[1][4]


See also

References

  1. 1.0 1.1 "Chemie und Pharmakologie von Steroidhormon-Estern" (in de). Z Vitam Horm Fermentforsch 9 (1–2): 97–143 contd. 1957. PMID 13531579. 
  2. "The interaction of C-17 esters of estradiol with the estrogen receptor". Endocrinology 114 (4): 1180–6. April 1984. doi:10.1210/endo-114-4-1180. PMID 6705734. 
  3. "Role of pocket flexibility in the modulation of estrogen receptor alpha by key residue arginine 394". Environ. Toxicol. Chem. 30 (2): 330–6. February 2011. doi:10.1002/etc.389. PMID 21038436. 
  4. 4.0 4.1 Friedrich W. Derz, ed (1976). ChemPRODUCTindex, Volumes 1-2. De Gruyter. pp. 881–. ISBN 978-3-11-002141-7. OCLC 2619908. https://books.google.com/books?id=KaAgAAAAMAAJ&pg=PA881.