Chemistry:FCE-24379

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FCE-24379 is a potent serotonin receptor antagonist related to the ergolines.[1] It antagonizes vascular serotonin receptors, which may correspond to the serotonin 5-HT2A receptor.[1] The drug is inactive against adrenergic receptors including the α1-, α2-, β1-, and β2-adrenergic receptors.[1] It produces hypotension in rodents.[1] FCE-24379 was first described in the scientific literature by 1988.[1]

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 "A new selective antagonist of vascular serotonin receptors lowers blood pressure in spontaneously hypertensive rats". Drugs 36 Suppl 1: 105–109. 1988. doi:10.2165/00003495-198800361-00019. PMID 3240722. 



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