Chemistry:Iproclozide
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Short description: Chemical compound
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| Routes of administration | Oral |
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| Formula | C11H15ClN2O2 |
| Molar mass | 242.70 g·mol−1 |
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Iproclozide (trade names Sursum, Sinderesin) is an irreversible and selective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was used as an antidepressant, but has since been discontinued.[1] It has been known to cause fulminant hepatitis and there have been at least three reported fatalities due to administration of the drug.[2][3]
See also
References
- ↑ "[Depressive states in a sanatorium milieu and monoamine oxidase inhibitors. (Therapeutic results by the combination of iproclozide and chlordiazepoxide). Apropos of 146 cases]". Journal de Medecine de Lyon 47 (96): 573–586. April 1966. PMID 5930723.
- ↑ "Iproclozide fulminant hepatitis. Possible role of enzyme induction". Gastroenterology 75 (3): 492–496. September 1978. doi:10.1016/0016-5085(78)90856-9. PMID 680506.
- ↑ Drug-induced liver disease. Informa Health Care. 2003. p. 455. ISBN 0-8247-0811-3.
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