Chemistry:Uldazepam

Short description: Chemical compound

Uldazepam

Clinical data
Other names	7-chloro-5-(2-chlorophenyl)-N-prop-2-enoxy-3H-1,4-benzodiazepin-2-amine
ATC code	none
Identifiers
IUPAC name (2Z)-7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one O-allyloxime
CAS Number	28546-58-9 N
PubChem CID	34274
ChemSpider	31577 Y
UNII	VAE9C0350C
KEGG	D06263 Y
Chemical and physical data
Formula	C18H15Cl2N3O
Molar mass	360.24 g·mol−1
3D model (JSmol)	Interactive image
SMILES Clc3ccccc3C/2=N/CC(=N/c1c\2cc(Cl)cc1)\NOC\C=C
InChI InChI=1S/C18H15Cl2N3O/c1-2-9-24-23-17-11-21-18(13-5-3-4-6-15(13)20)14-10-12(19)7-8-16(14)22-17/h2-8,10H,1,9,11H2,(H,22,23) Y Key:DTMPGSXFUXZBDK-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Uldazepam is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those of other benzodiazepines.

Synthesis

Thio thionamide is even more prone to amidine formation than the lactam itself.

Uldazepam synthesis: J. B. Hester, Jr., (1970); Chem. Abstr., 73: 99,001t (1970).

Reaction of thionamide (2) with O-allyl-hydroxylamine gave the oximino (3) uldazepam.

See also

• Benzodiazepine