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Short description: Chemical compound
Triflubazam |
Identifiers |
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1-methyl-5-phenyl-7-(trifluoromethyl)-1H-1,5-benzodiazepine-2,4(3H,5H)-dione
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Chemical and physical data |
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Formula | C17H13F3N2O2 |
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Molar mass | 334.298 g·mol−1 |
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3D model (JSmol) | |
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FC(F)(C1=CC(N(C2=CC=CC=C2)C(CC(N3C)=O)=O)=C3C=C1)F
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InChI=1S/C17H13F3N2O2/c1-21-13-8-7-11(17(18,19)20)9-14(13)22(16(24)10-15(21)23)12-5-3-2-4-6-12/h2-9H,10H2,1H3 YKey:DMNPCIKBNDKNTO-UHFFFAOYSA-N Y
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Triflubazam[1] is a drug which is a 1,5-benzodiazepine derivative, related to clobazam.[2] It has sedative and anxiolytic effects, with a long half-life and duration of action.[3][4][5]
See also
References
- ↑ Karl-Heinz Weber KH, Merz H, K Zeile, Giesemann R, Danneberg P, "5-Aryl-1H-1,5-benzodiazepine-2,4-diones", US patent 3660381, issued 2 May 1972, assigned to CH Boehringer Sohn AG and Co KG
- ↑ Lundbeck Institute (2003). "triflubazam". psychotropics.dk. http://www.psychotropics.dk/moleculeView/default.aspx?ID=1451&Catalogtype=A&ChapterID=1&Thissortorder=48.
- ↑ "Controlled clinical and quantitative EEG studies of triflubazam (ORF 8063) in patients with anxiety syndrome". Current Therapeutic Research, Clinical and Experimental 19 (3): 307–15. March 1976. PMID 5248.
- ↑ "Triflubazam (ORF 8063), a new benzodiazepine in anxiety neurosis.". Current Therapeutic Research 22: 166–171. 1977.
- ↑ "Effect of the 1,5-benzodiazepines, clobazam and triflubazam, on sleep in man". British Journal of Clinical Pharmacology 4 (5): 567–72. October 1977. doi:10.1111/j.1365-2125.1977.tb00787.x. PMID 20917.
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Others/unsorted |
- 3-Hydroxybutanal
- α-EMTBL
- AA-29504
- Avermectins (e.g., ivermectin)
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- DEABL
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- Loreclezole
- Menthyl isovalerate (validolum)
- Monastrol
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- Org 25,435
- Phenytoin
- Propanidid
- Retigabine (ezogabine)
- Safranal
- Seproxetine
- Stiripentol
- Sulfonylalkanes (e.g., sulfonmethane (sulfonal), tetronal, trional)
- Terpenoids (e.g., borneol)
- Topiramate
- Valerian constituents (e.g., isovaleric acid, isovaleramide, valerenic acid, valerenol)
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| Original source: https://en.wikipedia.org/wiki/Triflubazam. Read more |