Chemistry:Lofendazam

Short description: Chemical compound

Lofendazam

Clinical data
ATC code	none
Identifiers
IUPAC name 8-chloro-1-phenyl-1,3,4,5-tetrahydro- 2H-1,5-benzodiazepin- 2-one
CAS Number	29176-29-2 Y
PubChem CID	71709
ChemSpider	64759 Y
UNII	V7O53S50SN
Chemical and physical data
Formula	C15H13ClN2O
Molar mass	272.73 g·mol−1
3D model (JSmol)	Interactive image
SMILES Clc3ccc1c(N(C(=O)CCN1)c2ccccc2)c3
InChI InChI=1S/C15H13ClN2O/c16-11-6-7-13-14(10-11)18(15(19)8-9-17-13)12-4-2-1-3-5-12/h1-7,10,17H,8-9H2 Y Key:IUJQOUHDFKALCY-UHFFFAOYSA-N Y
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Lofendazam is an organic molecule which is a benzodiazepine derivative. Lofendazam is a 1,5-benzodiazepine, with the nitrogen atoms located at positions 1 and 5 of the diazepine ring; therefore, lofendazam is most closely related to other 1,5-benzodiazepines such as clobazam.

Lofendazam as a human pharmaceutical has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives. It is an active metabolite of another benzodiazepine, arfendazam.

See also

• Benzodiazepine
• Arfendazam
• Clobazam