Chemistry:Ciclotizolam

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Short description: Chemical compound
Ciclotizolam
Ciclotizolam structure.svg
Ball-and-stick model of the ciclotizolam molecule
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC20H18BrClN4S
Molar mass461.81 g·mol−1
3D model (JSmol)
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Ciclotizolam[1] (WE-973) is a drug which is a thienotriazolodiazepine derivative. It is a partial agonist for the benzodiazepine site of the GABAA receptor, with similar binding affinity to related compounds like brotizolam, but a low efficacy.[2][3]

See also

References

  1. DE Patent 2445430
  2. "Pharmacological and neurochemical properties of 1,4-diazepines with two annelated heterocycles ('hetrazepines')". European Journal of Pharmacology 109 (1): 19–31. February 1985. doi:10.1016/0014-2999(85)90535-7. PMID 2986988. 
  3. "Relative efficacies of 1,4-diazepines on GABA-stimulated chloride influx in rat brain vesicles". Life Sciences 45 (4): 349–58. 1989. doi:10.1016/0024-3205(89)90145-8. PMID 2569655.