Chemistry:Climazolam

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Short description: Anesthetic drug
Climazolam
Climazolam.svg
Clinical data
Trade namesClimasol
AHFS/Drugs.comInternational Drug Names
ATCvet code
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC18H13Cl2N3
Molar mass342.22 g·mol−1
3D model (JSmol)

Climazolam[1] (Ro21-3982) was introduced under licence as a veterinary medicine by the Swiss Pharmaceutical company Gräub under the tradename Climasol.[2] Climazolam is a benzodiazepine, specifically an imidazobenzodiazepine derivative developed by Hoffman-LaRoche. It is similar in structure to midazolam and diclazepam and is used in veterinary medicine for anesthetizing animals.[3][4]

References

  1. Walser A, Fryer RI, "Imidazodiazepines and processes therefor", US patent 4280957, issued 28 July 1981, assigned to Hoffman La Roche
  2. "Climazolam". Drugs.com. https://www.drugs.com/international/climazolam.html. 
  3. "Effect of ketamine and its combinations with xylazine and climazolam on the circulation and respiration in swine" (in German). Zentralbl Veterinarmed A 38 (7): 501–509. Aug 1991. doi:10.1111/j.1439-0442.1991.tb01041.x. PMID 1950241. 
  4. "Physiologic effects of anesthesia induced and maintained by intravenous administration of a climazolam-ketamine combination in ponies premedicated with acepromazine and xylazine". American Journal of Veterinary Research 57 (10): 1472–1477. Oct 1996. PMID 8896687.