Chemistry:Estradiol butyrylacetate
From HandWiki
Short description: Chemical compound
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| Trade names | Follikosid, Follikoside, Klimanosid |
| Other names | EBA; Estradiol 17β-butyrylacetate |
| Routes of administration | Intramuscular injection |
| Drug class | Estrogen; Estrogen ester |
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| Chemical and physical data | |
| Formula | C24H32O4 |
| Molar mass | 384.516 g·mol−1 |
| 3D model (JSmol) | |
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Estradiol butyrylacetate (EBA), sold under the brand names Follikosid and Klimanosid-R Depot (with testosterone ketolaurate and reserpine), is an estrogen medication which is no longer marketed.[1][2] It is an estrogen ester, specifically, an ester of estradiol.[1] It is administered by intramuscular injection and a single 10 mg dose has been said to have a duration of action of 2 to 3 weeks.[3][4] The excretion of EBA in women has been studied.[5][6]
See also
- Estradiol butyrylacetate/testosterone ketolaurate/reserpine
- List of estrogen esters § Estradiol esters
References
- ↑ 1.0 1.1 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. p. 898. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=RA1-PA129.
- ↑ "Hormone". Hagers Handbuch der Pharmazeutischen Praxis: Für Apotheker, Arzneimittelhersteller, Ärzte und Medizinalbeamte: Wirkstoffgruppen II Chemikalien und Drogen (A-AL). Springer-Verlag. 29 July 2013. pp. 157–. ISBN 978-3-662-25655-8. https://books.google.com/books?id=a2a0BgAAQBAJ&pg=PA157.
- ↑ Heinrich Kahr (8 March 2013). Konservative Therapie der Frauenkrankheiten: Anzeigen, Grenzen und Methoden Einschliesslich der Rezeptur. Springer-Verlag. pp. 20–. ISBN 978-3-7091-5694-0. https://books.google.com/books?id=Hte1BgAAQBAJ&pg=PA20.
- ↑ (in de) Hormontherapie in der Frauenheilkunde: Grundlagen und Praxis (5th ed.). de Gruyter. 1 January 1978. p. 276. ISBN 978-3110066647. OCLC 924728827.
- ↑ "Die Östrogenausscheidung im Zyklus und nach Injektion von Östradiolestern. Ein Beitrag zur Therapie mit Depotöstrogenen" (in de). Geburtshilfe Frauenheilkd 21: 868–78. September 1961. ISSN 0016-5751. PMID 13750804.
- ↑ "Über die Oestrogenausscheidung nach Injektion von Oestradiolestern" (in de). Gewebs-und Neurohormone: Physiologie des Melanophorenhormons. Springer, Berlin, Heidelberg. 1962. pp. 227–232. doi:10.1007/978-3-642-86860-3_24. ISBN 978-3-540-02909-0.
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