Chemistry:Racefemine

From HandWiki

Racefemine (INN), sold under the brand names Dysmalgine and Evalgin, is a uterine spasmolytic and muscle relaxant of the amphetamine family.[1][2][3][4][5] It is the racemic threo form of dextrofemine.[1][3] The drug acts as a β-adrenergic receptor agonist and sympathomimetic.[6] It appears to no longer be marketed.[7][8] Other tocolytics with similar chemical structures as phenethylamines or amphetamines include bedoradrine, buphenine, fenoterol, hexoprenaline, isoxsuprine, ritodrine, and terbutaline.[6][1]

References

  1. 1.0 1.1 1.2 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. 2014. pp. 804, others. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA804. Retrieved 9 October 2024. 
  2. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Netherlands. 2012. p. 244. ISBN 978-94-011-4439-1. https://books.google.com/books?id=tsjrCAAAQBAJ&pg=PA244. Retrieved 9 October 2024. 
  3. 3.0 3.1 The Extra Pharmacopoeia. Martindale Series. Pharmaceutical Press. 1993. p. 1408. ISBN 978-0-85369-300-0. https://books.google.com/books?id=EGZWAAAAYAAJ. Retrieved 9 October 2024. "Racefemine fumarate has been used as a uterine relaxant. The dextrorotatory isomer, dextrofemine, has been used intravenously." 
  4. Pharmaceutical Substances: Syntheses, Patents, Applications. Thieme. 2001. p. 1779. ISBN 978-1-58890-031-9. https://books.google.com/books?id=y25qAAAAMAAJ. Retrieved 9 October 2024. 
  5. Drugs: Synonyms and Properties. Routledge Revivals. Taylor & Francis. 2018. p. 451. ISBN 978-1-351-78990-5. https://books.google.com/books?id=dloPEAAAQBAJ&pg=PA451. Retrieved 9 October 2024. 
  6. 6.0 6.1 "Systemic Pharmacology of Adrenergic Activators and Inhibitors: Effects on the Genital System". Handbook of Experimental Pharmacology. 54 / 2. Berlin, Heidelberg: Springer Berlin Heidelberg. 1981. pp. 213–242. doi:10.1007/978-3-642-67584-3_5. ISBN 978-3-642-67586-7. 
  7. (in da) European Drug Index: European Drug Registrations (Fourth ed.). Taylor & Francis. 1997. p. 412. ISBN 978-1-351-44947-2. https://books.google.com/books?id=GCBiEAAAQBAJ&pg=PA412. Retrieved 9 October 2024. 
  8. Schweizerischer Apotheker-Verein (2000). Index Nominum 2000: International Drug Directory. Medpharm Scientific Publishers. ISBN 978-3-88763-075-1. https://books.google.com/books?id=5GpcTQD_L2oC. Retrieved 9 October 2024.