Chemistry:Salmefamol
From HandWiki
Salmefamol (INN, BAN; developmental code name AH-3923) is a drug of the phenethylamine and amphetamine families described as a bronchodilator which was never marketed.[1] It is a β-adrenergic receptor agonist with some selectivity for the β2-adrenergic receptor[2][3] and has been described as a "sister compound" to salbutamol.[4] However, the drug is more potent (1.5-fold), longer-acting (6 hours), and more lipophilic in comparison to salbutamol.[5][6] It was intended for inhalational or intravenous administration.[6] Salmefamol was first described in the literature by 1968.[1]
References
- ↑ 1.0 1.1 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. 2014. p. 1089. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA1089. Retrieved 17 October 2024.
- ↑ "Structure-activity relationships as a response to the pharmacological differences in beta-receptor ligands". American Journal of Hypertension 2 (11 Pt 2): 245S–251S. November 1989. doi:10.1093/ajh/2.11.245s. PMID 2573372.
- ↑ "β-Adrenergic receptor subtypes". Trends in Pharmacological Sciences (Elsevier BV) 2: 18–20. 1981. doi:10.1016/0165-6147(81)90248-0. ISSN 0165-6147.
- ↑ Organic Chemistry. OUP Oxford. 2012. p. 530. ISBN 978-0-19-927029-3. https://books.google.com/books?id=kQgu2j_ber0C&pg=PA530. Retrieved 17 October 2024.
- ↑ Kummer, F. (2012). Treatment of Asthma: The long-acting beta-2-agonists. Springer Vienna. p. 38. ISBN 978-3-7091-7513-2. https://books.google.com/books?id=LNNeBAAAQBAJ&pg=PT38. Retrieved 17 October 2024.
- ↑ 6.0 6.1 An Introduction to Medicinal Chemistry. Oxford University Press. 2017. p. 665. ISBN 978-0-19-874969-1. https://books.google.com/books?id=bBqeDgAAQBAJ&pg=PA665. Retrieved 17 October 2024.
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