Chemistry:Dextrofemine
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Dextrofemine (INN), sold under the brand names Marsyl and Dysmalgine, is a uterine spasmolytic and muscle relaxant of the amphetamine family.[1][2][3][4][5] It is the dextrorotatory enantiomer of racefemine.[1][2] The drug acts as a β-adrenergic receptor agonist and sympathomimetic.[6] It was marketed in France in 1966 but appears to no longer be marketed.[3][7][8] Other tocolytics with similar chemical structures as phenethylamines or amphetamines include bedoradrine, buphenine, fenoterol, hexoprenaline, isoxsuprine, ritodrine, and terbutaline.[6][1]
See also
- Phenoxyethylamine
References
- ↑ 1.0 1.1 1.2 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. 2014. pp. 804, others. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA804. Retrieved 9 October 2024.
- ↑ 2.0 2.1 The Extra Pharmacopoeia. Martindale Series. Pharmaceutical Press. 1993. p. 1408. ISBN 978-0-85369-300-0. https://books.google.com/books?id=EGZWAAAAYAAJ. Retrieved 9 October 2024. "Racefemine fumarate has been used as a uterine relaxant. The dextrorotatory isomer, dextrofemine, has been used intravenously."
- ↑ 3.0 3.1 Drugs Available Abroad: A Guide to Therapeutic Drugs Available and Approved for Use Outside the U. S.. Gale Research, Derwent Publications Inc.. 1990. p. 61. ISBN 978-0-8103-7177-4. https://books.google.com/books?id=2x1tAAAAMAAJ. Retrieved 9 October 2024. "268. Dextrofemine. Countries Where Available and Release Dates: France (1966). Brand Names and Manufactgurers: Base: Dysmalgine—Clin-Midy (France). Drug Action: Spasmolytic; uterine relaxant."
- ↑ Organic-chemical Drugs and Their Synonyms: (an International Survey). Akad.-Verlag. 1994. p. 1470. ISBN 978-3-05-500156-7. https://books.google.com/books?id=SwltAAAAMAAJ. Retrieved 9 October 2024. "Dextrofemine, Dysmalgine injectable , Marsyl U Uterine spasmolytic , muscle relaxant"
- ↑ "[Doppler umbilical artery velocimetry during labor in normal pregnancies]" (in French). J Gynecol Obstet Biol Reprod (Paris) 19 (1): 48–52. 1990. PMID 2313067.
- ↑ 6.0 6.1 "Systemic Pharmacology of Adrenergic Activators and Inhibitors: Effects on the Genital System". Handbook of Experimental Pharmacology. 54 / 2. Berlin, Heidelberg: Springer Berlin Heidelberg. 1981. pp. 213–242. doi:10.1007/978-3-642-67584-3_5. ISBN 978-3-642-67586-7.
- ↑ (in da) European Drug Index: European Drug Registrations, Fourth Edition. Taylor & Francis. 1997. p. 412. ISBN 978-1-351-44947-2. https://books.google.com/books?id=GCBiEAAAQBAJ&pg=PA412. Retrieved 9 October 2024.
- ↑ Schweizerischer Apotheker-Verein (2000). Index Nominum 2000: International Drug Directory. Medpharm Scientific Publishers. ISBN 978-3-88763-075-1. https://books.google.com/books?id=5GpcTQD_L2oC. Retrieved 9 October 2024.
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