Chemistry:Methylallyltryptamine

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Use and effects

MALT was not included in Alexander Shulgin's 1997 book TiHKAL (Tryptamines I Have Known and Loved).[1] However, years after the book's publication, he described MALT as having important unexplored potential as a psychedelic drug.[2] Subsequently, MALT was encountered as a novel designer drug.[3] It has been reported to have been used at doses of 25 to 50 mg via routes including oral, smoking, or vaping.[3] The drug's effects have been described as comparable to those of methylpropyltryptamine (MPT) but less pronounced.[3]

Interactions

Pharmacology

Pharmacodynamics

MALT is a serotonin receptor modulator and has been found to interact with the serotonin 5-HT1A, 5-HT2A, and 5-HT2C receptors.[4]

Chemistry

Analogues

Analogues of MALT include 4-HO-MALT, 4-AcO-MALT, 5-MeO-MALT, diallyltryptamine (DALT), methylpropyltryptamine (MPT), and methylisopropyltryptamine (MiPT), among others.

History

MALT was first described in the scientific literature by Niels Jensen of the University of Göttingen by 2004.[4] The drug was subsequently first encountered as a novel designer drug by 2018.[3]

Society and culture

MALT Crystals
A ziplock bag containing 100mg of MALT crystals, labeled "Not for human consumption".

MALT is not explicitly scheduled in any countries; however, it could be considered a psychoactive substance under the United Kingdom Psychoactive Substances Act, which requires the prosecutor to prove that the substance is psychoactive in order for a person to be charged with an offense.[5] It could also be considered a structural analogue of a scheduled substance under the United States Federal Analogue Act due to its similarity to scheduled tryptamines. It is not a controlled substance in Canada as of 2025.[6]

See also

References

  1. Shulgin, Alexander; Shulgin, Ann (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN 0-9630096-9-9. OCLC 38503252. http://www.erowid.org/library/books_online/tihkal/tihkal.shtml. 
  2. "Alexander Shulgin (1925–2014)". The Fabulist (5). 2014. https://isomerdesign.com/bitnest/external/Fabulist/5. "On that day in 2010, Alexander Shulgin was sitting outside under a parasol in his front yard surrounded by admirers, looking very happy, and talking discursively about the unexplored potential in 5-ethoxylated tryptamines and asymmetrical N-allyl-tryptamines such as MAlT, EAlT, PAlT, and iPAlT". 
  3. 3.0 3.1 3.2 3.3 "MALT" (in ru). https://aipsin.com/newsubstance/568/. 
  4. 4.0 4.1 Jensen N (2004). Tryptamines as Ligands and Modulators of the Serotonin 5‑HT2A Receptor and the Isolation of Aeruginascin from the Hallucinogenic Mushroom Inocybe aeruginascens (PDF) (Thesis). Georg-August-University Göttingen. doi:10.53846/goediss-2111.
  5. "Psychoactive Substances Act Guidance". The Crown Prosecution Service. https://www.release.org.uk/sites/default/files/pdf/Psychoactive%20Substances%20Act%20Guidance.pdf. 
  6. "Controlled Drugs and Substances Act". https://laws-lois.justice.gc.ca/eng/acts/c-38.8/FullText.html.