Chemistry:7-Chloro-AMT

7-Chloro-AMT
Identifiers
	IUPAC name 1-(7-chloro-1H-indol-3-yl)propan-2-amine;
CAS Number	711-99-9 ;
PubChem CID	13900;
ChemSpider	13298;
Chemical and physical data
Formula	C11H13ClN2
Molar mass	208.69 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(CC1=CNC2=C1C=CC=C2Cl)N;
	InChI InChI=1S/C11H13ClN2/c1-7(13)5-8-6-14-11-9(8)3-2-4-10(11)12/h2-4,6-7,14H,5,13H2,1H3; Key:OHEYTFPYHFDAJQ-UHFFFAOYSA-N;

Short description: Chemical compound

7-Chloro-α-methyltryptamine (7-Cl-AMT) is a tryptamine derivative with stimulant effects, invented in the 1960s. It is a weak monoamine oxidase inhibitor but its pharmacology has not otherwise been studied by modern techniques, though several closely related compounds are known to act as serotonin–dopamine releasing agents and agonists of the 5-HT_2A receptor.^[1]^[2]^[3]

References

↑ Hofmann A, Troxler F, "New indole derivatives and their preparation", FR patent 1344579, published 29 November 1963, assigned to Sandoz SA.
↑ Robert VJ, Jackson HO, "7-Chloro-alpha-methyltryptamine derivatives.", US patent 3282959, issued 1 November 1966, assigned to Parke-Davis.
↑ "Alpha-ethyltryptamines as dual dopamine-serotonin releasers". Bioorganic & Medicinal Chemistry Letters 24 (19): 4754–4758. October 2014. doi:10.1016/j.bmcl.2014.07.062. PMID 25193229.

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Identifiers

IUPAC name 1-(7-chloro-1H-indol-3-yl)propan-2-amine
CAS Number	711-99-9^Y
PubChem CID	13900
ChemSpider	13298
Chemical and physical data
Formula	C₁₁H₁₃ClN₂
Molar mass	208.69 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC(CC1=CNC2=C1C=CC=C2Cl)N
InChI InChI=1S/C11H13ClN2/c1-7(13)5-8-6-14-11-9(8)3-2-4-10(11)12/h2-4,6-7,14H,5,13H2,1H3 Key:OHEYTFPYHFDAJQ-UHFFFAOYSA-N