Chemistry:SL88.0338

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SL88.0338 is a serotonergic drug with a benzoylpiperidine structure, which is used in scientific research. It acts as a potent and selective 5-HT1A receptor antagonist. It is used for basic research into the action and behavioural effects of 5-HT1A receptor activation and inactivation.[1][2][3][4]

See also

References

  1. ↑ "Behavioural profiles in the mouse defence test battery suggest anxiolytic potential of 5-HT(1A) receptor antagonists". Psychopharmacology 144 (2): 121–130. May 1999. doi:10.1007/s002130050984. PMID 10394992. 
  2. ↑ "The effects of compounds varying in selectivity as 5-HT(1A) receptor antagonists in three rat models of anxiety". Neuropharmacology 39 (10): 1848–1857. July 2000. doi:10.1016/s0028-3908(00)00074-5. PMID 10884565. 
  3. ↑ "SSR181507, a dopamine D2 receptor antagonist and 5-HT1A receptor agonist. II: Behavioral profile predictive of an atypical antipsychotic activity". Neuropsychopharmacology 28 (11): 1889–1902. November 2003. doi:10.1038/sj.npp.1300261. PMID 12902993. 
  4. ↑ "SSR181507, a dopamine D₂ receptor and 5-HT(₁A) receptor ligand: evidence for mixed anxiolytic- and antidepressant-like activities". Pharmacology, Biochemistry, and Behavior 97 (3): 428–435. January 2011. doi:10.1016/j.pbb.2010.09.019. PMID 20920519. 



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