Chemistry:α-Hydroxyetizolam

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Short description: Chemical compound

α-Hydroxyetizolam
Alpha-hydroxyetizolam.svg
Clinical data
Other namesα-Hydroxyetizolam
Dependence
liability
Moderate
Routes of
administration
Oral, sublingual, rectal
Pharmacokinetic data
MetabolismHepatic
Elimination half-life8.2 hours[1]
ExcretionKidney
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC17H15ClN4OS
Molar mass358.84 g·mol−1
3D model (JSmol)

α-Hydroxyetizolam is the pharmacologically active metabolite of etizolam.[2] α-Hydroxyetizolam has a half-life of approximately 8.2 hours.[3]

Etizolam's other non-pharmacologically active metabolite in humans is 8-hydroxyetizolam.[2]

See also


References

  1. "Single and multiple dose pharmacokinetics of etizolam in healthy subjects". European Journal of Clinical Pharmacology 40 (2): 181–185. 1991-02-01. doi:10.1007/BF00280074. PMID 2065698. 
  2. 2.0 2.1 "alpha-Hydroxyetizolam" (in en). PubChem. U.S. National Library of Medicine. https://pubchem.ncbi.nlm.nih.gov/compound/15135972. 
  3. "Case report: Etizolam and its major metabolites in two unnatural death cases". Forensic Science International 182 (1–3): e1-6. November 2008. doi:10.1016/j.forsciint.2008.08.012. PMID 18976871. 

External links