Chemistry:α-Hydroxyetizolam
From HandWiki
Short description: Chemical compound
![]() | |
Clinical data | |
---|---|
Other names | α-Hydroxyetizolam |
Dependence liability | Moderate |
Routes of administration | Oral, sublingual, rectal |
Pharmacokinetic data | |
Metabolism | Hepatic |
Elimination half-life | 8.2 hours[1] |
Excretion | Kidney |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
Chemical and physical data | |
Formula | C17H15ClN4OS |
Molar mass | 358.84 g·mol−1 |
3D model (JSmol) | |
| |
|
α-Hydroxyetizolam is the pharmacologically active metabolite of etizolam.[2] α-Hydroxyetizolam has a half-life of approximately 8.2 hours.[3]
Etizolam's other non-pharmacologically active metabolite in humans is 8-hydroxyetizolam.[2]
See also
- Etizolam
- Alprazolam
- Brotizolam
- Clotiazepam
- Deschloroetizolam
- Metizolam
- Benzodiazepine dependence
- Benzodiazepine withdrawal syndrome
- Long-term effects of benzodiazepines
References
- ↑ "Single and multiple dose pharmacokinetics of etizolam in healthy subjects". European Journal of Clinical Pharmacology 40 (2): 181–185. 1991-02-01. doi:10.1007/BF00280074. PMID 2065698.
- ↑ 2.0 2.1 "alpha-Hydroxyetizolam" (in en). PubChem. U.S. National Library of Medicine. https://pubchem.ncbi.nlm.nih.gov/compound/15135972.
- ↑ "Case report: Etizolam and its major metabolites in two unnatural death cases". Forensic Science International 182 (1–3): e1-6. November 2008. doi:10.1016/j.forsciint.2008.08.012. PMID 18976871.
External links
![]() | Original source: https://en.wikipedia.org/wiki/Α-Hydroxyetizolam.
Read more |