Chemistry:Saripidem

Short description: Chemical compound

Saripidem

Clinical data
ATC code	none
Identifiers
IUPAC name N-[[2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]methyl]-N-methylbutanamide
CAS Number	103844-86-6 N
PubChem CID	3058746
ChemSpider	2319846 Y
UNII	0J6174G60N
ChEMBL	ChEMBL73416 Y
Chemical and physical data
Formula	C19H20ClN3O
Molar mass	341.84 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(N(C)Cc1c(nc2ccccn12)c3ccc(Cl)cc3)CCC
InChI InChI=1S/C19H20ClN3O/c1-3-6-18(24)22(2)13-16-19(14-8-10-15(20)11-9-14)21-17-7-4-5-12-23(16)17/h4-5,7-12H,3,6,13H2,1-2H3 Y Key:LIFDPEORUVTOCP-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Saripidem is a sedative and anxiolytic drug in the imidazopyridine family, which is related to the better known drugs zolpidem and alpidem.

Saripidem has a similar pharmacological profile to the benzodiazepine family of drugs including sedative and anxiolytic properties, but its chemical structure is quite different from that of the benzodiazepine drugs, and saripidem is described as a nonbenzodiazepine.

The mechanism of action by which saripidem produces its sedative and anxiolytic effects is by modulating the benzodiazepine binding site on GABA_A receptors, however unlike many older GABA_A agonists, saripidem is highly subtype selective and binds primarily to the ω1 subtype.