Chemistry:N1-Methyl-lysergic acid diethylamide

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Short description: Chemical compound
N1-Methyl-lysergic acid diethylamide
MLD-41.svg
Clinical data
Other namesMLD-41; N1-Methyl-Lysergic Acid Diethylamide
Routes of
administration
Oral
Pharmacokinetic data
MetabolismHepatic
ExcretionRenal
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC21H27N3O
Molar mass337.467 g·mol−1
3D model (JSmol)
  (verify)

N1-Methyl-lysergic acid diethylamide (MLD-41) is a derivative of LSD that has about one-third the psychoactive effects. It has been studied in cross-tolerance of LSD.[1]

Metabolism of other 1-methylated-ergoloids to their secondary amine derivatives has been frequently noted in mammals.[2]

References

  1. "Production of cross-tolerance to psychosis-producing doses of lysergic acid diethylamide and psilocybin.". The Journal of Psychology 49 (1): 151–4. January 1960. doi:10.1080/00223980.1960.9916396. 
  2. "Methylergometrine, an active metabolite of methysergide". Cephalalgia: An International Journal of Headache 6 (1): 35–41. March 1986. doi:10.1046/j.1468-2982.1986.0601035.x. PMID 3698092.