Chemistry:CS-27349

From HandWiki
Short description: Chemical compound
CS-27349
CS-27349.svg
Identifiers
CAS Number
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H25NO3
Molar mass351.446 g·mol−1
3D model (JSmol)

CS-27349, or L-2-α-tropinyl benzilate, is an experimental incapacitating agent. It acts as an antagonist to muscarinic acetylcholine receptors, causing delirium. It has 37% of the potency of the related compound 3-quinuclidinyl benzilate (BZ) in producing peripheral effects, but 85% of the potency in producing central effects. The mean dose required to incapacitate subjects was 1.2 times that of BZ.[1] It has not been in use since the 1970s, and there have been no publications about its effects or long-term toxicology since then.[2]

References

  1. "Dual Use Research of Concern: Derivatives of 3-Quinuclidinyl Benzilate". Military Medical Science Letters 84 (1): 2–41. 2015. doi:10.31482/mmsl.2015.001. 
  2. Assessment of Potential Long-Term Health Effects on Army Human Test Subjects of Relevant Biological and Chemical Agents, Drugs, Medications and Substances (Report). Ho-Chunk Technical Solutions Healthcare Division. February 29, 2016. https://apps.dtic.mil/sti/pdfs/AD1009505.pdf.