Chemistry:2-Bromomescaline

From HandWiki
Short description: Mescaline derivative drug
Not to be confused with 2C-B (sometimes also referred to as "bromomescaline")
2-Bromomescaline
2-BRM structure.png
Clinical data
ATC code
  • none
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC11H16BrNO3
Molar mass290.157 g·mol−1
3D model (JSmol)

2-Bromomescaline (2-Br-M) is a derivative of the phenethylamine hallucinogen mescaline which has an unusual 2-bromo substitution.[1][2] It is an agonist for serotonin receptors, with a binding affinity of 215 nM at 5-HT1A, 513 nM at 5-HT2A and 379 nM at 5-HT2C, so while it is around ten times more tightly binding than mescaline at 5-HT1A and 5-HT2A receptors, it is over twenty times more potent at 5-HT2C.[3]

See also

References

  1. ↑ The Shulgin Index. Volume 1. Psychedelic Phenethylamines and Related Compounds. Transform Press. 2011. p. 280–281, 355. ISBN 978-0-9630096-3-0. 
  2. ↑ "A novel synthesis of aromatic methoxy and methylenedioxy substituted 2,3,4,5-tetrahydro-1H3-benzazepines". Journal of Heterocyclic Chemistry 9 (3): 609–616. June 1972. doi:10.1002/jhet.5570090322. 
  3. ↑ Phenethylamine Von der Struktur zur Funktion. Nachtschatten Verlag AG. 2013. pp. 908–910. ISBN 978-3-03788-700-4. 



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