Chemistry:25C-NBOH

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25C-NBOH (2C-C-NBOH, NBOH-2CC) is a psychedelic drug and derivative of the phenethylamine derived hallucinogen 2C-C. It has similar serotonin receptor affinity to the better-known compound 25C-NBOMe.[1][2] The drug has been encountered as a novel designer drug.[3]

Use and effects

25C-NBOH is said to have a dose of 100 to 750 μg sublingually and an onset of up to 45 minutes.[3]

Interactions

Chemistry

Analogues and derivatives

Analytical chemistry

25C-NBOH undergoes degradation under routine Gas Chromatography (GC) conditions, as well as other NBOH's substances, into 2C-C.[4][5] An alternative method proposed for reliable identification of 25I-NBOH using GC/MS may be used for 25C-NBOH analysis.[6][7]

Society and culture

Canada

25C-NBOH is a controlled substance in Canada under phenethylamine blanket-ban language.[8]

United Kingdom

This substance is a Class A drug in the United Kingdom as a result of the N-benzylphenethylamine catch-all clause in the Misuse of Drugs Act 1971.[9]


See also

  • 25-NB (psychedelics)

References

  1. ↑ "Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists". ACS Chemical Neuroscience 5 (3): 243–9. March 2014. doi:10.1021/cn400216u. PMID 24397362. 
  2. ↑ Hansen M (2010-12-16). Design and Synthesis of Selective Serotonin Receptor Agonists for Positron Emission Tomography Imaging of the Brain (Ph.D. thesis). University of Copenhagen. doi:10.13140/RG.2.2.33671.14245.
  3. ↑ 3.0 3.1 "25C-NBOH" (in ru). https://aipsin.com/newsubstance/523/. 
  4. ↑ "2A receptor agonist identified in blotter paper seizures in Brazil". Forensic Toxicology 35 (2): 408–414. 2017. doi:10.1007/s11419-017-0357-x. PMID 28706567. 
  5. ↑ "Identification of new NBOH drugs in seized blotter papers: 25B-NBOH, 25C-NBOH, and 25E-NBOH". Forensic Toxicology 38 (2): 203–215. 2019. doi:10.1007/s11419-019-00509-7. 
  6. ↑ "Preventing misidentification of 25I-NBOH as 2C-I on routine GC–MS analyses". Forensic Toxicology 35 (2): 415–420. 2017. doi:10.1007/s11419-017-0362-0. http://eprints.lincoln.ac.uk/26957/7/25i-nboh%20aceito.pdf. 
  7. ↑ "Identification of new NBOH drugs in seized blotter papers: 25B-NBOH, 25C-NBOH, and 25E-NBOH". Forensic Toxicology 38 (2): 203–215. 2019. doi:10.1007/s11419-019-00509-7. 
  8. ↑ "Controlled Drugs and Substances Act". https://laws-lois.justice.gc.ca/eng/acts/c-38.8/FullText.html. 
  9. ↑ "The Misuse of Drugs Act 1971 (Ketamine etc.) (Amendment) Order 2014" (in en). http://www.legislation.gov.uk/uksi/2014/1106/made. 



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