Chemistry:Estradiol disulfate
From HandWiki
Short description: Chemical compound
| |
| Names | |
|---|---|
| IUPAC name
[(8R,9S,13S,14S,17S)-13-Methyl-3-sulfooxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] hydrogen sulfate
| |
| Other names
E2DS; Estradiol 3,17β-disulfate
| |
| Identifiers | |
3D model (JSmol)
|
|
| ChEMBL | |
| ChemSpider | |
| KEGG | |
PubChem CID
|
|
| |
| |
| Properties | |
| C18H24O8S2 | |
| Molar mass | 432.50 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Tracking categories (test):
Estradiol disulfate (also known as E2DS or estradiol 3,17β-disulfate) is an endogenous estrogen conjugate and metabolite of estradiol.[1] It is related to estradiol 3-sulfate and estradiol 17β-sulfate.[1] Estradiol disulfate has 0.0004% of the relative binding affinity of estradiol for the estrogen receptor alpha (ERα), one of the two estrogen receptors (ERs).[2]
See also
References
- ↑ 1.0 1.1 Herr, F.; Revesz, C.; Manson, A. J.; Jewell, J. B. (1970), Bernstein, Seymour; Solomon, Samuel, eds., "Biological Properties of Estrogen Sulfates" (in en), Chemical and Biological Aspects of Steroid Conjugation (Berlin, Heidelberg: Springer): pp. 368–408, doi:10.1007/978-3-642-95177-0_8, ISBN 978-3-642-95177-0
- ↑ "Hands-off linear interaction energy approach to binding mode and affinity estimation of estrogens". J Chem Inf Model 53 (10): 2681–8. October 2013. doi:10.1021/ci400392p. PMID 24063761.
 |  |
