Biology:LPAR5
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Lysophosphatidic acid receptor 5 also known as LPA5 is a protein that in humans is encoded by the LPAR5 gene.[1][2][3][4][5] LPA5 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).[6]
See also
References
- ↑ White, Kenneth E.; Evans, Wayne E.; O'Riordan, Jeffery L.H.; Speer, Marcy C.; Econs, Michael J.; Lorenz-Depiereux, Bettina; Grabowski, Monika; Meitinger, Thomas et al. (Dec 2000). "Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23". Nat Genet 26 (3): 345–8. doi:10.1038/81664. PMID 11062477.
- ↑ "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene 275 (1): 83–91. Sep 2001. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.
- ↑ "GPR92 as a new G12/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5". J Biol Chem 281 (33): 23589–97. Aug 2006. doi:10.1074/jbc.M603670200. PMID 16774927.
- ↑ "Lysophosphatidic acid binds to and activates GPR92, a G protein-coupled receptor highly expressed in gastrointestinal lymphocytes". J Pharmacol Exp Ther 318 (2): 619–28. Jul 2006. doi:10.1124/jpet.105.098848. PMID 16651401.
- ↑ "Entrez Gene: GPR92 G protein-coupled receptor 92". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57121.
- ↑ "LPA Receptors: Subtypes and Biological Actions". Annual Review of Pharmacology and Toxicology 50 (1): 157–186. January 2010. doi:10.1146/annurev.pharmtox.010909.105753. PMID 20055701.
Further reading
- "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. 2002. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878.
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