Biology:GPR45
From HandWiki
Short description: Protein-coding gene in humans
 Generic protein structure example |
Probable G-protein coupled receptor 45 is a protein that in humans is encoded by the GPR45 gene.[1][2]
This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system.[2]
References
- ↑ "Discovery of three novel orphan G-protein-coupled receptors". Genomics 56 (1): 12–21. May 1999. doi:10.1006/geno.1998.5655. PMID 10036181.
- ↑ 2.0 2.1 "Entrez Gene: GPR45 G protein-coupled receptor 45". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11250.
Further reading
- "Brain-specific expression of novel G-protein-coupled receptors, with homologies to Xenopus PSP24 and human GPR45". Biochem. Biophys. Res. Commun. 276 (3): 952–6. 2000. doi:10.1006/bbrc.2000.3569. PMID 11027574.
- "Mammalian PSP24s (alpha and beta isoforms) are not responsive to lysophosphatidic acid in mammalian expression systems". Biochem. Biophys. Res. Commun. 276 (3): 957–64. 2000. doi:10.1006/bbrc.2000.3570. PMID 11027575.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature 434 (7034): 724–31. 2005. doi:10.1038/nature03466. PMID 15815621. Bibcode: 2005Natur.434..724H.
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