Biology:ELTD1

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

EGF, latrophilin and seven transmembrane domain-containing protein 1 is a latrophilin-like orphan receptor of the adhesion G protein-coupled receptor family. In humans this protein is encoded by the ELTD1 gene.[1][2] ELTD1 appears to have a role in angiogenesis,[3] both physiological and pathological in cancer.[4]

See also

  • Latrophilin

References

  1. "ETL, a novel seven-transmembrane receptor that is developmentally regulated in the heart. ETL is a member of the secretin family and belongs to the epidermal growth factor-seven-transmembrane subfamily". The Journal of Biological Chemistry 276 (6): 4150–7. February 2001. doi:10.1074/jbc.M004814200. PMID 11050079. 
  2. "Entrez Gene: ELTD1 EGF, latrophilin and seven transmembrane domain containing 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64123. 
  3. "A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis". Cancer Cell 24 (2): 229–41. August 2013. doi:10.1016/j.ccr.2013.06.004. PMID 23871637. 
  4. "Epidermal growth factor, latrophilin, and seven transmembrane domain-containing protein 1 marker, a novel angiogenesis marker". OncoTargets and Therapy 8: 3767–74. December 2015. doi:10.2147/OTT.S93843. PMID 26719704. 

Further reading