Biology:GPRC5B

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

G-protein coupled receptor family C group 5 member B is a protein that in humans is encoded by the GPRC5B gene.[1][2][3]

Function

The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade.[3]

See also

References

  1. "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics 60 (3): 295–308. Nov 1999. doi:10.1006/geno.1999.5927. PMID 10493829. 
  2. "Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain". Genomics 65 (2): 121–8. Jul 2000. doi:10.1006/geno.2000.6164. PMID 10783259. 
  3. 3.0 3.1 "Entrez Gene: GPRC5B G protein-coupled receptor, family C, group 5, member B". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51704. 

Further reading

  • "Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C)". Genomics 67 (1): 8–18. 2001. doi:10.1006/geno.2000.6226. PMID 10945465. 

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.