Biology:P2RY13
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
P2Y purinoceptor 13 is a protein that in humans is encoded by the P2RY13 gene.[1][2][3]
The product of this gene, P2Y13, belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. Two transcript variants encoding the same protein have been identified for this gene.[3]
See also
References
- ↑ "An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors". J Mol Biol 307 (3): 799–813. Mar 2001. doi:10.1006/jmbi.2001.4520. PMID 11273702.
- ↑ "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene 275 (1): 83–91. Sep 2001. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.
- ↑ 3.0 3.1 "Entrez Gene: P2RY13 purinergic receptor P2Y, G-protein coupled, 13". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=53829.
Further reading
- "Identification of a novel human ADP receptor coupled to G(i).". J. Biol. Chem. 276 (44): 41479–85. 2001. doi:10.1074/jbc.M105912200. PMID 11546776.
- "P2Y(13): identification and characterization of a novel Galphai-coupled ADP receptor from human and mouse.". J. Pharmacol. Exp. Ther. 301 (2): 705–13. 2002. doi:10.1124/jpet.301.2.705. PMID 11961076.
- "Identification of G protein-coupled receptor genes from the human genome sequence.". FEBS Lett. 520 (1–3): 97–101. 2002. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "P2Y13 receptor is critical for reverse cholesterol transport". Hepatology 52 (4): 1477–83. 2010. doi:10.1002/hep.23897. PMID 20830789.
External links
- "P2Y Receptors: P2Y13". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=3034.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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