Biology:OPN1MW

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Green-sensitive opsin is a protein that in humans is encoded by the OPN1MW gene. OPN1MW2 is a similar opsin.

The OPN1MW gene provides instructions for making an opsin pigment that is more sensitive to light in the middle of the visible spectrum (yellow/green light).

See also

• Opsin
• OPN1LW

Further reading

• "Molecular biology of the visual pigments". Vision Res. 26 (12): 1881–95. 1987. doi:10.1016/0042-6989(86)90115-X. PMID 3303660. 
• "Defective colour vision associated with a missense mutation in the human green visual pigment gene". Nat. Genet. 1 (4): 251–6. 1993. doi:10.1038/ng0792-251. PMID 1302020. 
• "Analysis of fusion gene and encoded photopigment of colour-blind humans". Nature 342 (6250): 679–82. 1990. doi:10.1038/342679a0. PMID 2574415. 
• "Molecular genetics of human color vision: the genes encoding blue, green, and red pigments". Science 232 (4747): 193–202. 1986. doi:10.1126/science.2937147. PMID 2937147. Bibcode: 1986Sci...232..193N. 
• "Rod photoreceptor neurite sprouting in retinitis pigmentosa". J. Neurosci. 15 (8): 5429–38. 1995. doi:10.1523/JNEUROSCI.15-08-05429.1995. PMID 7643192. 
• "A new mechanism in blue cone monochromatism". Hum. Genet. 98 (4): 403–8. 1996. doi:10.1007/s004390050229. PMID 8792812. 
• "Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin". Nature 383 (6601): 637–40. 1996. doi:10.1038/383637a0. PMID 8857542. Bibcode: 1996Natur.383..637F. 
• "Large-scale production and purification of the human green cone pigment: characterization of late photo-intermediates". Biochem. J. 330 (3): 1201–8. 1998. doi:10.1042/bj3301201. PMID 9494086. 
• "Regional expression of disease-related genes in human and monkey retina". Mol. Vis. 4: 24. 1998. PMID 9815288. 
• "Position of a 'green-red' hybrid gene in the visual pigment array determines colour-vision phenotype". Nat. Genet. 22 (1): 90–3. 1999. doi:10.1038/8798. PMID 10319869. 
• "Novel missense mutations in red/green opsin genes in congenital color-vision deficiencies". Biochem. Biophys. Res. Commun. 294 (2): 205–9. 2002. doi:10.1016/S0006-291X(02)00458-8. PMID 12051694. Bibcode: 2002BBRC..294..205U. 
• "GRK1-dependent phosphorylation of S and M opsins and their binding to cone arrestin during cone phototransduction in the mouse retina". J. Neurosci. 23 (14): 6152–60. 2003. doi:10.1523/JNEUROSCI.23-14-06152.2003. PMID 12853434. 
• "Abnormal distribution of red/green cone opsins in a patient with an autosomal dominant cone dystrophy". Ophthalmic Genet. 26 (2): 69–76. 2005. doi:10.1080/13816810590968041. PMID 16020309. 

External links

• GeneReviews/NIH/NCBI/UW entry on Red-Green Color Vision Defects