Biology:Neuropeptide FF receptor 2

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Neuropeptide FF receptor 2, also known as NPFF2 and formerly as GPR74, is a human protein encoded by the NPFFR2 gene.

See also

• Neuropeptide FF receptor

Further reading

• "Sequence and tissue distribution of a novel G-protein-coupled receptor expressed prominently in human placenta.". Biochem. Biophys. Res. Commun. 256 (2): 352–6. 1999. doi:10.1006/bbrc.1999.0332. PMID 10079187. 
• "Molecular cloning and characterisation of GPR74 a novel G-protein coupled receptor closest related to the Y-receptor family.". Brain Res. Mol. Brain Res. 77 (2): 199–208. 2000. doi:10.1016/S0169-328X(00)00052-8. PMID 10837915. 
• "Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor.". J. Biol. Chem. 275 (34): 25965–71. 2000. doi:10.1074/jbc.M004515200. PMID 10851242. 
• "Identification and characterization of two G protein-coupled receptors for neuropeptide FF.". J. Biol. Chem. 275 (50): 39324–31. 2001. doi:10.1074/jbc.M004385200. PMID 11024015. 
• "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• "Characterization of the NPGP receptor and identification of a novel short mRNA isoform in human hypothalamus.". Regul. Pept. 111 (1–3): 21–9. 2003. doi:10.1016/S0167-0115(02)00220-3. PMID 12609745. 
• "Functional properties of Pfr(Tic)amide and BIBP3226 at human neuropeptide FF2 receptors". Peptides 24 (12): 1947–54. 2004. doi:10.1016/j.peptides.2003.10.009. PMID 15127947. 
• "Neuropeptide FF (NPFF) analogs functionally antagonize opioid activities in NPFF2 receptor-transfected SH-SY5Y neuroblastoma cells". Mol. Pharmacol. 67 (3): 965–75. 2005. doi:10.1124/mol.104.004614. PMID 15608144. 
• "Regulation of endogenous human NPFF2 receptor by neuropeptide FF in SK-N-MC neuroblastoma cell line". J. Neurochem. 96 (2): 573–84. 2006. doi:10.1111/j.1471-4159.2005.03581.x. PMID 16336216. 
• "Alternative splicing of human and mouse NPFF2 receptor genes: Implications to receptor expression". FEBS Lett. 580 (30): 6955–60. 2007. doi:10.1016/j.febslet.2006.11.063. PMID 17157836. 
• "A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis". Am. J. Hum. Genet. 80 (6): 1115–24. 2007. doi:10.1086/518445. PMID 17503329. 

External links

• "Neuropeptide FF Receptors: NPFF2". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=3001.