Biology:ELTD1
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Short description: Protein-coding gene in the species Homo sapiens
Generic protein structure example |
EGF, latrophilin and seven transmembrane domain-containing protein 1 is a latrophilin-like orphan receptor of the adhesion G protein-coupled receptor family. In humans this protein is encoded by the ELTD1 gene.[1][2] ELTD1 appears to have a role in angiogenesis,[3] both physiological and pathological in cancer.[4]
See also
- Latrophilin
References
- ↑ "ETL, a novel seven-transmembrane receptor that is developmentally regulated in the heart. ETL is a member of the secretin family and belongs to the epidermal growth factor-seven-transmembrane subfamily". The Journal of Biological Chemistry 276 (6): 4150–7. February 2001. doi:10.1074/jbc.M004814200. PMID 11050079.
- ↑ "Entrez Gene: ELTD1 EGF, latrophilin and seven transmembrane domain containing 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64123.
- ↑ "A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis". Cancer Cell 24 (2): 229–41. August 2013. doi:10.1016/j.ccr.2013.06.004. PMID 23871637.
- ↑ "Epidermal growth factor, latrophilin, and seven transmembrane domain-containing protein 1 marker, a novel angiogenesis marker". OncoTargets and Therapy 8: 3767–74. December 2015. doi:10.2147/OTT.S93843. PMID 26719704.
Further reading
- "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors". Genomics 84 (1): 23–33. July 2004. doi:10.1016/j.ygeno.2003.12.004. PMID 15203201.
- "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". Journal of Proteome Research 4 (6): 2070–80. 2006. doi:10.1021/pr0502065. PMID 16335952.
- "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research 16 (1): 55–65. January 2006. doi:10.1101/gr.4039406. PMID 16344560.
Original source: https://en.wikipedia.org/wiki/ELTD1.
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