Biology:TAS2R50
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 Generic protein structure example |
Taste receptor type 2 member 50 is a protein that in humans is encoded by the TAS2R50 gene.[1][2][3][4]
Function
TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway.[2] See also TAS2R10.[4]
See also
References
- ↑ "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet 32 (3): 397–401. Oct 2002. doi:10.1038/ng1014. PMID 12379855.
- ↑ 2.0 2.1 "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet Genome Res 98 (1): 45–53. Feb 2003. doi:10.1159/000068546. PMID 12584440.
- ↑ "Identification of Four Gene Variants Associated with Myocardial Infarction". Am J Hum Genet 77 (4): 596–605. Sep 2005. doi:10.1086/491674. PMID 16175505.
- ↑ 4.0 4.1 "Entrez Gene: TAS2R50 taste receptor, type 2, member 50". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=259296.
Further reading
- Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
- "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. 2002. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982.
- "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell 112 (3): 293–301. 2003. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520.
- "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. 2005. doi:10.1093/molbev/msi027. PMID 15496549.
- "Lineage-Specific Loss of Function of Bitter Taste Receptor Genes in Humans and Nonhuman Primates". Genetics 170 (1): 313–26. 2006. doi:10.1534/genetics.104.037523. PMID 15744053.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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