Biology:TAS2R8

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Taste receptor type 2 member 8 is a protein that in humans is encoded by the TAS2R8 gene.[1][2][3]

Function

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.[3]

See also

References

  1. "A novel family of mammalian taste receptors". Cell 100 (6): 693–702. Apr 2000. doi:10.1016/S0092-8674(00)80705-9. PMID 10761934. 
  2. "A family of candidate taste receptors in human and mouse". Nature 404 (6778): 601–4. Apr 2000. doi:10.1038/35007072. PMID 10766242. 
  3. 3.0 3.1 "Entrez Gene: TAS2R8 taste receptor, type 2, member 8". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50836. 

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.