Biology:GPR116

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Probable G-protein coupled receptor 116 is a protein that in humans is encoded by the GPR116 gene.[1][2][3] GPR116 has now been shown to play an essential role in the regulation of lung surfactant homeostasis.[4][5]

References

  1. Stacey, edited by S Yona, M Stacey (2010). Adhesion-GPCRs : structure to function. New York: Springer Science+Business Media. ISBN 978-1-4419-7912-4. 
  2. "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Letters 531 (3): 407–14. Nov 2002. doi:10.1016/S0014-5793(02)03574-3. PMID 12435584. 
  3. "Entrez Gene: GPR116 G protein-coupled receptor 116". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=221395. 
  4. "Essential regulation of lung surfactant homeostasis by the orphan G protein-coupled receptor GPR116". Cell Reports 3 (5): 1457–64. May 2013. doi:10.1016/j.celrep.2013.04.019. PMID 23684610. 
  5. "Lung surfactant levels are regulated by Ig-Hepta/GPR116 by monitoring surfactant protein D". PLOS ONE 8 (7): e69451. 2013. doi:10.1371/journal.pone.0069451. PMID 23922714. Bibcode2013PLoSO...869451F. 

Further reading