Biology:Super Conserved Receptor Expressed in Brain
From HandWiki
Short description: Protein family
| G protein-coupled receptor 27 | |
|---|---|
| Identifiers | |
| Symbol | GPR27 |
| Alt. symbols | SREB1 |
| NCBI gene | 2850 |
| HGNC | 4482 |
| OMIM | 605187 |
| RefSeq | NM_018971 |
| UniProt | Q9NS67 |
| Other data | |
| Locus | Chr. 3 p21-p14 |
| G protein-coupled receptor 85 | |
|---|---|
| Identifiers | |
| Symbol | GPR85 |
| Alt. symbols | SREB2 |
| NCBI gene | 54329 |
| HGNC | 4536 |
| OMIM | 605188 |
| RefSeq | NM_018970 |
| UniProt | P60893 |
| Other data | |
| Locus | Chr. 7 q31 |
| G protein-coupled receptor 173 | |
|---|---|
| Identifiers | |
| Symbol | GPR173 |
| Alt. symbols | SREB3 |
| NCBI gene | 54328 |
| HGNC | 18186 |
| OMIM | 300253 |
| RefSeq | NM_018969 |
| UniProt | Q9NS66 |
| Other data | |
| Locus | Chr. X p11 |
The Super Conserved Receptor Expressed in Brain (SREB) family are a group of related G-protein coupled receptors.[1] Since no endogenous ligands have yet been identified for these receptors, they are classified as orphan receptors. Receptors within the group include SREB1 (GPR27), SREB2 (GPR85), and SREB3 (GPR173).[2]
References
- ↑ "An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system". Biochem. Biophys. Res. Commun. 272 (2): 576–82. 2000. doi:10.1006/bbrc.2000.2829. PMID 10833454.
- ↑ National Center for Biotechnology Information, [https://www.ncbi.nlm.nih.gov/Structure/cdd/cd15216 Conserved Protein Domain Family 7tmA_SREB1_GPR27], accessed 5 February 2022
External links
- IUPHAR GPCR Database - GPR27 (previously SREB1)
- IUPHAR GPCR Database - GPR85 (previously SREB2)
- IUPHAR GPCR Database - GPR173 (previously SREB3)
- GPR27+protein at the US National Library of Medicine Medical Subject Headings (MeSH)
- GPR85+receptor at the US National Library of Medicine Medical Subject Headings (MeSH)
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