Chemistry:Butanserin

From HandWiki

Butanserin (INN; developmental code name R-53393) is a serotonin 5-HT2 receptor antagonist and α1-adrenergic receptor antagonist which was studied as an antihypertensive agent but was never marketed.[1][2][3] It was first described in the scientific literature by 1984.[1][2][3]

See also

References

  1. 1.0 1.1 Elks, J. (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA195. Retrieved 16 January 2026. 
  2. 2.0 2.1 "Antagonism of the antidiarrhoeal effect of clonidine and the lethal effect of noradrenaline in rats: a reliable procedure to evaluate the in-vivo alpha 1- and alpha 2-blocking activity of drugs?". J Pharm Pharmacol 36 (8): 516–520. August 1984. doi:10.1111/j.2042-7158.1984.tb04442.x. PMID 6148393. 
  3. 3.0 3.1 "Characterization of flufylline, fluprofylline, ritanserin, butanserin and R 56413 with respect to in-vivo alpha 1-,alpha 2- and 5-HT2-receptor antagonism and in-vitro affinity for alpha 1-,alpha 2- and 5-HT2-receptors: comparison with ketanserin". J Pharm Pharmacol 38 (5): 374–379. May 1986. doi:10.1111/j.2042-7158.1986.tb04590.x. PMID 2872314.